Expertise

Areas of expertise

Our teams are equipped and organized to efficiently and cost-effectively support, coordinate and manage clinical research projects, in all phases; proof of concept, First-in-Human phase I to phase IV, observational and registry studies, and in a wide variety of indications.

Most recent experience/indications were in the area of Liver diseases (PBC, Biliary Atresia, NASH), alpha 1- antitrypsin deficiency, Pulmonology/Cardiology (Pulmonary Arterial Hypertension, CTEPH, IPF), Oncology (advanced/metastatic solid tumors, prostate cancer), Food Allergy (Peanut), Phase I, dermatology, gastroenterology and Septic Shock.

Below is a full overview of our experience.

Therapeutic Clinical Trial Experience

Orphan Indications
  • Pulmonary Hypertension
  • Chronic Thromboembolic Pulmonary Hypertension
  • Enzyme replacement therapy
  • Primary Biliary Cirrhosis
  • Primary Sclerosing Cholangitis
  • Familial Adenomatous Polyposis
  • Alpha-1 Antitrypsin Deficiency
  • Peanut allergy
Paediatric studies
  • Paediatric Pulmonary Arterial Hypertension
  • Biliary Atresia
  • Peanut allergy
Cardiovascular Interventional
  • Hypertension
  • Unstable Angina
  • Myocardial Infarction
  • Left Ventricular Heart Failure
  • Pulmonary Hypertension
  • Coronary Artery Bypass Graft Surgery
  • Catecholamine Resistant Hypotension
Cardiovascular Devices
  • Drug eluting stent
  • Renal ablation
  • Abdominal Aortic Aneurism
  • Aortic valve replacement (TAVI)
Oncology
  • Metastatic Colorectal cancer
  • Solid Tumors
  • Non Hodgkin Lymphoma
  • Breast, Ovarian, Pancreatic, Prostate, Colorectal, NSCLC, SCLC
  • Familial Adenomatous Polyposis
  • Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
  • Phase I dose escalating study in adult patients with advanced/metastatic solid tumours
  • Systemic B-cell lymphoma
  • Mucosa-associated lymphoid tissue (MALT) Lymphoma
  • Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Dermatology
  • Cutaneous warts
  • Atopic dermatitis
  • Solid Tumors
  • Usual type vulvar intraepithelial neoplasia
Phase I studies
  • Phase I SD/MD PK/PD healthy volunteers studies
  • Benign Prostate Hypertrophy
  • Phase I SAD/MAD PK/PD studies
Other Indications
  • Graft versus Host Disease, stem cell
  • Relapsing Remitting Multiple Sclerosis
  • Psoriasis
  • Idiopatic Pulmonary Fibrosis
  • Acute Kidney Injury
  • Aneurismal Subarachnoidal Bleeding
  • Scleroderma
  • Portal Hypertension
  • Systemic Sclerosis
  • HPV-induced genital lesions
  • Septic Shock